As John from Powerline put it:
Yet the Supreme Court has expanded the scope of the clause beyond all recognition, to the point where it has rendered the most basic principle of the Constitution, that our national government is one of limited and enumerated powers, almost a nullity. Michael Ramirez illustrates graphically how one clause, misinterpreted in pursuit of a Progressive agenda, can shred the constitutional structure of which it is intended to be only one small part.
(H/T: Powerline)